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Antimicrobial-Steroid Treatment of Active Pulmonary Tuberculosis as a Routine Measure
HENRIETTE MARCUS, M.D.;
PANAYOTIS CHRISTOPOULOS, M.D.
AMA Arch Intern Med. 1960;105(4):542-559.
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Introduction
Since the introduction of corticosteroid preparations in 1950, many contributions in the American, and particularly in the foreign literature, have dealt with the effect of these compounds on tuberculosis. Some of the pertinent papers have recently been reviewed by Des Prez and Organick.1 The communications can be divided, roughly, into several periods. The first, from 1950 to 1953, dealt with (a) the temporary beneficial effects of steroid hormones on patients severely ill with pulmonary tuberculosis,2 (b) the deleterious effect of steroid hormones in experimental tuberculosis,3,4 (c) the untoward effects of steroid hormones on existing tuberculosis,5 and (d) the occurrence of serious tuberculosis, often miliary, in patients not previously ill with the disease, who were under treatment with steroids for other conditions.6
In 1953, and in subsequent years, there began to appear articles on the beneficial effects of steroid hormone therapy in conjunction with antimicrobial therapy in the treatment of
. . . [Full Text PDF of this Article]
Author Affiliations
Mount Vernon, N.Y.
From the Nathan B. Van Etten Hospital of the Bronx Municipal Hospital Center, New York, and the Division of Tuberculosis and Chest Diseases, Grasslands Hospital, Valhalla, N.Y.
Footnotes
Submitted for publication April 17, 1959.
Prednisolone used in this study was supplied by William Gittinger, M.D., of Pfizer and Company.
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