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Their Similarity to Those Observed in Myocardial Infarction

HERSCHEL SANDBERG, M.D.; BYONG SOK MIN, M.D.; LEONARD FEINBERG, Ph.D.; SAMUEL BELLET, M.D.

AMA Arch Intern Med. 1960;105(6):866-872.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

When Thannhauser and Stanley^1,2 fed I¹³¹-labeled olive oil and followed the appearance and disappearance of the radioactivity in the blood of their patients, they introduced a new, simple, and very valuable technique for the study of neutral fat metabolism in health and disease. Numerous reports soon followed^3-6 in which I¹³¹-labeled neutral fat was used as a diagnostic tool in various malabsorptive syndromes. The fruitfulness of this field of investigation probably led to a delay in the use of this technique in studying hyperlipemic states, although the original workers reported abnormal curves in nephrotics and idiopathic hyperlipemia as well.^1,2 Recent studies by others as well as in our laboratory ^7-9 have demonstrated that individuals with proven myocardial infarction display elevated levels of blood radioactivity following ingestion of a radioactively labeled fat meal. Since it is well known that patients with diabetes mellitus have a tendency to develop atherosclerotic lesions at an . . . [Full Text PDF of this Article]

Author Affiliations
Philadelphia With the Technical Assistance of Miss Jean Schraeder

From the Division of Cardiology, Philadelphia General Hospital.; Chief, Radioisotope Section (Dr. Sandberg); Resident (Dr. Min); Chief, Chemical Research Laboratory (Dr. Feinberg), Division of Cardiology, Philadelphia General Hospital. Director, Division of Cardiology, Philadelphia General Hospital, and Director, Division of Cardiovascular Disease, Graduate Hospital of the University of Pennsylvania (Dr. Bellet).

Footnotes
Submitted for publication Sept. 11, 1959.

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