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J. THOMAS DOWLING, M.D.; FREDERICK F. BECKER, M.D.

AMA Arch Intern Med. 1960;105(6):884-890.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Despite widespread use of potassium iodide and syrup of hydriodic acid in pulmonary disease, goiter and myxedema are rare and only recently described complications of iodide therapy. The possibility exists that when hypothyroidism and goiter do develop during treatment with iodide-containing medicine, some preexisting defect in thyroidal metabolism may result in marked sensitivity to an antithyroid action of iodide. In an attempt to demonstrate such an abnormality, several techniques have been applied to the study of a patient who developed flagrant myxedema during prolonged ingestion of syrup of hydriodic acid.

Report of a Case

A 67-year-old white widow was admitted to the hospital because of lethargy, intolerance to cold, and hoarseness. One year prior to admission she developed a chronic cough for which she was given syrup of hydriodic acid. Although her cough subsided, she continued to take 6 teaspoonfuls of the syrup daily (420 mg. of hydriodic acid) until . . . [Full Text PDF of this Article]

Author Affiliations
Los Angeles; Boston

From the Thorndike Memorial Laboratory and Second and Fourth (Harvard) Medical Services, Boston City Hospital, the Department of Medicine, Harvard Medical School, Boston, the Department of Medicine, Veterans Administration Center, Los Angeles, and the Department of Medicine, University of California Medical Center, Los Angeles.; Fellow in Pathology, Department of Pathology, New York University College of Medicine, and formerly Intern, Second and Fourth Medical (Harvard) Services, Boston City Hospital (Dr. Becker).

Footnotes
Submitted for publication July 31, 1959.

Supported in part by research grant No. A-267 from the National Institute of Arthritis and Metabolic Diseases of the National Institutes of Health, Public Health Service and in part by the Medical Research and Development Board, Office of the Surgeon General, Department of the Army, under Contract No. DA-49-007-MD-412.

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