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Report of a Case Treated with Amphotericin B

LYNN A. BERNARD, M.D.; JOHN C. OWENS, M.D.

Arch Intern Med. 1960;106(1):101-111.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The association of cryptococcosis with diseases involving the reticuloendothelial system is well known. Of 243 cases of cryptococcosis reviewed by Collins, Gelhorn, and Trimble,¹ 51, or approximately 25%, were associated with the presence of Hodgkin's disease, lymphosarcoma, or leukemia. Many isolated reports exist in the literature relative to the development of disseminated cryptococcosis in patients with advanced malignant disease of all types. However, the coexistence of cryptococcal infection with Boeck's sarcoid has been encountered rather infrequently. Collins,² in reviewing the subject of bone involvement in cryptococcosis, reported on three such cases, two of which were shown later to have had cryptococcosis alone. Gandy³ described a case of cutaneous cryptococcosis in a patient with proven sarcoidosis of several years' duration. Heller⁴ and others described a case of disseminated, nonmeningitic cryptococcal infection in a patient with well-documented preexisting Boeck's sarcoid. The first overt manifestation of the fungus infection in this case was . . . [Full Text PDF of this Article]

Author Affiliations
Houston, Texas

From the Medical Service of Hermann Hospital and the Department of Medicine, Baylor University College of Medicine, Houston, Texas.

Footnotes
Submitted for publication Sept. 3, 1959.

Attending Physician, Hermann Hospital, and Clinical Associate Professor of Medicine, Baylor University College of Medicine (Dr. Bernard); Resident in Medicine, Hermann Hospital, and Clinical Assistant in Medicine, Baylor University College of Medicine (Dr. Owens).

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