This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (3)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Reliability and Prognostic Value of Chemical and Radioactive Iodine Studies

CAPTAIN JACK DOMNITZ, MC; MAJOR H. F. HURD, MC; JOSEPH W. GOLDZIEHER, M.D.

Arch Intern Med. 1960;106(2):194-204.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The availability of radioactive iodine has unquestionably revolutionized the diagnosis and therapy of thyroid disease. There is less certainty, however, as to the value and meaning of I¹³¹ diagnostic studies in the hyperthyroid patient following surgery or the administration of therapeutic doses of radioiodine. Goldsmith,¹ in 1954, stated that the thyroidal radioiodine uptake cannot be interpreted in the usual way following treatment with radioiodine; Chapman, Maloof, Maisterrena, and Martin ² observed that the thyroid I¹³¹ uptake was at times disproportionately low when compared to the clinical status, while others ^3,4 noted persistently elevated thyroid uptakes or PBI¹³¹ values in clinically euthyroid patients. Nodine and his collaborators ⁵ have further documented this problem with six cases in which there was a discrepancy between the clinical status and diagnostic tests with the use of I¹³¹. On the other hand, Schultz and Zieve⁶ maintained that the thyroidal I¹³¹ uptake and PBI are prognostically . . . [Full Text PDF of this Article]

Author Affiliations
US Army; San Antonio, Texas

From the Department of Medicine and Radiology Service, Brooke General Hospital, Fort Sam Houston, Texas, and the Department of Endocrinology, Southwest Foundation for Research and Education, San Antonio, Texas.

Footnotes
Submitted for publication Feb. 4, 1960.

Presented as "Chemical and Radioactive Iodine Studies Following I131 Therapy of Hyperthyroidism," at the American Medical Association Clinical Meeting in Dallas, Texas, Dec. 4, 1959.

Resident Physician, Department of Medicine (Dr. Domnitz), and Chief, Radioisotopic Clinic, Radiology Service (Dr. Hurd), Brooke General Hospital, Brooke Army Medical Center, Fort Sam Houston, Texas. Dr. Goldzieher is Chairman of the Department of Endocrinology, Southwest Foundation for Research and Education, San Antonio, Texas.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?