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WALTER LYON BLOOM, M.D.; WILLIAM MITCHELL, Jr.

Arch Intern Med. 1960;106(3):321-326.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

It is apparent from recent studies on fasting as an introduction to the treatment of obesity ¹ that the weight loss in fasting patients was greater than could be explained on a caloric basis. Preliminary studies indicated that salt excretion significantly exceeded that observed in patients on low-salt diets. The potential importance of these observations was obvious, and quantitative studies were performed on fasting obese patients in an attempt to elucidate the unexplained weight loss.

Benedict's² early studies on Levanzin, the professional faster, indicated that weight loss in fasting was greatest during the early fast period. Gamble, Ross, and Tisdale³ suggested that early in fasting there was a loss of extracellular fluid, loss of water from reduction in cell volume and water loss from metabolism of cell substance, and these multiple factors accounted for the weight loss in excess of caloric expenditure.

Gamble^4,5 and Hervey and McCance . . . [Full Text PDF of this Article]

Author Affiliations
Atlanta; Baltimore

From the Research Center, Piedmont Hospital, Atlanta.

Footnotes
Submitted for publication Dec. 4, 1959.

Supported in part by a grant from the Georgia Heart Association.

Mr. Mitchell's present address: Senior Class, Johns Hopkins Medical School.

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