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Hyperkalemia Associated with the Myeloproliferative Disorder
RALPH M. MYERSON, M.D.;
ABRAHAM M. FRUMIN, M.D.
Arch Intern Med. 1960;106(4):479-482.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Elevated serum potassium levels unassociated with manifestations of hyperkalemia have been observed in patients with thrombocythemia associated with the myeloproliferative disorder.1-3 Studies indicate that potassium released from platelets during the process of blood coagulation is responsible, since serum prepared from platelet-free plasma has a normal potassium concentration. "Spurious hyperkalemia" has been suggested as a term for this syndrome.3 We wish to reemphasize these findings with additional observations.
Results and Comment
Table 1 lists the clinical and laboratory data in a group of patients with elevations of leukocytes, erythrocytes, and platelets alone or in various combinations. Significant elevations of serum potassium levels above the normal level of 5 mEq. per liter were noted in Patients 1, 4, 5, 6, 7, 8, 9, and 14. In each of these patients there was a significant elevation of the platelet count. In the absence of thrombocythemia, elevations of the leukocyte or erythrocyte
. . . [Full Text PDF of this Article]
Author Affiliations
Philadelphia
From the Department of Medicine, Veterans Administration Hospital, Philadelphia; Department of Medicine, Woman's Medical College of Pennsylvania, and Department of Laboratories, Albert Einstein Medical Center, Southern Division.
Footnotes
Submitted for publication Jan. 21, 1960.
Assistant Chief, Medical Service, Veterans Administration Hospital, and Clinical Professor of Medicine, Woman's Medical College of Pennsylvania (Dr. Myerson); Assistant Professor of Medicine, Woman's Medical College of Pennsylvania and Assistant in Pathology (Hematology) Albert Einstein Medical Center, Southern Division (Dr. Frumin).
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