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ALBERT N. BREST, M.D.; ALEX E. PEARCE, M.D.; WILLIAM LIKOFF, M.D.

Arch Intern Med. 1960;106(6):859-861.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The association of multiple cutaneous angiomata and limb hypertrophy as a distinct clinical entity, rather than a coincidental combination of two unrelated anomalies, was first described by Trelat and Monad in 1896. Klippel and Trenaunay subsequently described this rare syndrome as "nevus variqueux osteohypertrophique"; and in a series of papers beginning in 1918, Parkes Weber ^1-5 discussed the problem of hemangiectatic hypertrophy of limbs. Since that time a few other case reports of this syndrome have been reported.^6-9 However, the apparent rarity of this disorder and the interesting speculative relationship with several other obscure entities, including Maffucci's syndrome, have prompted this report.

Report of a Case

A 16-year-old white youth was admitted for treatment of a chronic leg ulcer which had its origin six months previously following an episode of minor trauma to the right lower leg. The patient gave a history of previous poor healing of wounds incurred . . . [Full Text PDF of this Article]

Author Affiliations
Philadelphia

Footnotes
Submitted for publication Dec. 16, 1959.

Instructor in Medicine (Cardiology) (Dr. Brest); Assistant Professor of Surgery (Dr. Pearce), Professor of Medicine and Chief, Cardiovascular Section (Dr. Likoff), Hahnemann Medical College and Hospital.

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