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Recovery After General Exposure to 1082 Roentgens of Co60 Radiation at 36 Roentgens Per Hour

E. DONNALL THOMAS; EMERY C. HERMAN; JOE H. CANNON; OTTO D. SAHLER; JOSEPH W. FERREBEE; H. E. M. KAY; M. CONSTANTOULAKIS

Arch Intern Med. 1961;107(3):395-400.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The question of what is a lethal dose of whole-body radiation for man is doubtless compounded by factors of age, sex, state of health, and nature of treatment given following exposure. The question is, however, of some pertinence since it affects plans for medical care following radiation disaster as well as the proper selection of treatment for patients that suffer marrow aplasia following therapeutic radiation exposures. In the infant reported here, marrow function returned following a midline air dose of 1,082 roentgens. The treatments given and the implications of the results obtained are discussed.

Report of Case

The patient, a 5-month-old female infant, was admitted to the hospital on February 8, 1959, because of an illness of one week characterized by pallor and petechiae. Physical examination showed enlargement of the spleen and liver. The white blood cell count was 258,000 per cubic millimeter, and 98% of these were blast cells . . . [Full Text PDF of this Article]

Author Affiliations
COOPERSTOWN, N.Y.; LONDON, ENGLAND

From the Mary Imogene Bassett Hospital (affiliated with Columbia University), Cooperstown.; Department of Clinical Pathology, Royal Marsden Hospital and Institute of Cancer Research, Fulham Road, London.

Footnotes
Submitted for publication April 29, 1960.

Supported by a grant from the Medical Research Council of Great Britain. Dr. Constantoulakis is in receipt of a Gordon Jacobs Research Fellowship.

Supported by a grant from the John A. Hartford Foundation, Inc.; Research Grant C-2643 from the United States Public Health Service; and by Contract AT(30-1)-2005 from the United States Atomic Energy Commission.

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