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A Report of Four Cases

PHILIP M. JOHNSON, M.D.; W. GEOFFREY WYSOR, JR., M.D.; CHAPEL HILL, N.C.

Arch Intern Med. 1961;108(3):370-375.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

Of the various diverticula arising in the gastrointestinal tract, those occurring in the jejunum have seldom stimulated great clinical interest. Typically asymptomatic, jejunal diverticula give rise only rarely to nonspecific complications such as perforation and hemorrhage. However, as is now established, jejunal diverticula have the unique potentiality of simulating certain clinical syndromes. The association of such diverticula with megaloblastic anemia and malabsorption has enlarged the differential diagnosis and the clinical management of these conditions.

Since 1949, twenty-five cases of jejunal diverticulosis, megaloblastic anemia, and/or intestinal malabsorption have been reported,^* reflecting both the infrequency and the increasing recognition of the syndrome.^4-21 Jejunal diverticulosis, invariably present, has frequently been associated with other intestinal diverticula. Of these cases the predominant finding was anemia or defective absorption of Vitamin B₁₂ in 9, steatorrhea in 3, and combinations of these abnormalities in the remainder. The bone marrow was megaloblastic in 16 of . . . [Full Text PDF of this Article]

Author Affiliations
Assistant Professor, Department of Radiology (Dr. Johnson), and Instructor, Department of Medicine (Dr. Wysor), The School of Medicine, University of North Carolina.

Footnotes
Submitted for publication Aug. 29, 1960.

This investigation was supported by Grant No. A-3207 (CI) of the National Institutes of Health.

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