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Cause of Portal Hypertension and Liver Failure; Review

GEORGE H. PORTER, M.D.

Arch Intern Med. 1961;108(3):483-495.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The development of knowledge validating sarcoidosis as a distinct clinicopathologic entity has been traced and reviewed.^* The purpose of this study is to review the incidence of hepatic sarcoidosis, its relationship to liver failure with jaundice, ascites, and portal hypertension, and to add to the literature 2 cases of portal hypertension and 2 cases of liver failure without portal hypertension, all secondary to intrinsic hepatic sarcoidosis.

Report of Cases

Case 1.—

A 41-year-old Negro woman complained of abdominal distention, weight loss, and anorexia of 3 months' duration. Past history was negative for jaundice, liver disease, or alcoholism.

Physical examination revealed scleral icterus, normal fundi, and no lymph node enlargement. The liver was palpated 8 cm. below the right costal margin, was firm and nontender. The spleen was felt 4 cm. below the left costal margin. A fluid wave and shifting dullness were demonstrated, and there was 1+ pitting edema of . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

Present address: National Cancer Institute, Bethesda, Md.; From the Departments of Medicine, Washington University School of Medicine, Barnes Hospital, St. Louis, and Duke University Medical Center, Durham, N.C.

Footnotes
Submitted for publication May 26, 1960.

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