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Megaloblastic Anemia in Association with Jejunal Diverticula
DONALD W. CRAWFORD, M.D.;
RICHARD M. FREEMAN, M.D.
Arch Intern Med. 1961;108(5):775-780.
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In 1930 Taylor described a case of jejunal diverticulosis associated with pernicious anemia.1 Since that time, macrocytic anemia with intestinal diverticula has been described in 18 additional cases.2-14 In 8 of these, gastric acid was demonstrated, thus essentially excluding Addisonian pernicious anemia. In 9 of the cases, achlorhydria or "nearly complete achlorhydria" was noted; in 2 reports, the presence of gastric acid was not mentioned13,14 (Table 1). This report describes another case of non-Addisonian megaloblastic anemia apparently due to small bowel diverticulosis.
Report of a Case
An 85-year-old retired white carpenter was admitted to Palo Alto-Stanford Hospital Center on Sept. 30, 1959, with the history of diarrhea and weight loss of 4 years' duration.
Present Illness.—
In 1955 he was seen by his physician because of a prolonged episode of diarrhea. At that time his red cell count was 4,400,000 per cu. mm., hematocrit was 43%, and
. . . [Full Text PDF of this Article]
Author Affiliations
PALO ALTO, CALIF.
Residents in Medicine, Department of Medicine, Stanford University School of Medicine, San Francisco (Dr. Crawford and Dr. Freeman).
Footnotes
Submitted for publication Aug. 22, 1960.
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