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Unusual Fibrous Connective Tissue Growth Associated; Review of Literature and Discussion of Possible Physiological Mechanisms Involved in These Changes

SCOTT R. INKLEY, M.D.; GEORGE R. ABBOTT, M.D.

Arch Intern Med. 1961;108(6):903-915.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

An extensive fibrous connective tissue proliferation suggestive of retroperitoneal fibrosis or chronic mediastinitis is reported here. Aside from being the most extensive involvement that we can find after reviewing the literature, this lesion produced a most interesting natural experiment in the development of pulmonary arteriosclerosis. This change was unilateral and associated with complete obstruction of the pulmonary vein on the involved side. Although there have been several case reports of pulmonary vein obstruction in association with a similar lesion, none of these has been unilateral and unaccompanied by cor pulmonale.

Report of Case

His first admission was in 1951, at age 39, because of a history of hemoptysis which was of 9 years' duration. In 1942 he had gone to Arizona for several months following a period of heavy cough, mild hemoptysis, fever, and weight loss from which he made an uneventful recovery. Chest x-rays at that time are said . . . [Full Text PDF of this Article]

Author Affiliations
CLEVELAND

Assistant Professor of Medicine, Department of Medicine, Western Reserve University and University Hospitals of Cleveland (Dr. Inkley); Fellow in Pathology, Western Reserve University, Institute of Pathology (Dr. Abbott).

Footnotes
Submitted for publication Oct. 4, 1960.

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