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Potentiation by Antibiotics and Steroids

WILLIAM L. BENDEL, JR., M.D.; GEORGE J. RACE, M.D.

Arch Intern Med. 1961;108(6):916-924.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A review of the recent literature reveals surprisingly few reports of the clinical syndrome of aplastic anemia associated with disseminated visceral candidiasis (moniliasis); in fact, an extensive search revealed only one other reported case, although it seems certain that such scarcity is due to lack of reporting rather than to rarity of the condition.

Gausewitz, Jones, and Worley 1 in 1951 reported the case of a 10-year-old white male with hypoplastic anemia, weight loss, and chronic cough. Candida albicans was cultured from the sputum following treatment with penicillin, streptomycin, and chloramphenicol. The disease process continued its chronic course, and the patient died 5 months after the onset of symptoms. At autopsy, there was candidial infiltration in the myocardium, thyroid gland, kidneys, and lungs; positive cultures for C. albicans were obtained from the spleen and lungs. The fungal lesions were very similar to those seen in the present case report; i.e., . . . [Full Text PDF of this Article]

Author Affiliations
DALLAS, TEXAS

Department of Pathology, Baylor University Medical Center.

Footnotes
Submitted for publication Oct. 18, 1960.

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