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A Report of a Case and Review of the Literature

JEROME G. PORUSH, M.D.; ABNER J. DELMAN, M.D.; MARTIN M. FEUER, M.D.

Arch Intern Med. 1962;109(3):302-309.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In recent years there have been numerous reports and reviews of the various kinds of familial, nonhemolytic and nonobstructive hyperbilirubinemia in the adult. Basically, these cases can be divided into two main categories. The first group is made up of those cases in whom the elevated bilirubin is mainly unconjugated (indirect), and they, consequently, have no bile in the urine. Gilbert et al.^1-3 described a group of patients in this category, and since then there have been numerous reviews of this syndrome published under a variety of names.^4-8 The second group is composed of patients who have elevated levels of both conjugated (direct) and unconjugated (indirect) bilirubin in their serum. These patients frequently have bilirubinuria. Patients of this variety were first described by Dubin and Johnson⁹ and Sprinz and Nelson,¹⁰ and a rather extensive review of this syndrome (chronic idiopathic jaundice or the Dubin-Johnson syndrome) appeared . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Department of Medicine, The Mount Sinai Hospital, New York.; U.S.P.H.S. Research Fellow, Department of Medicine, The Mount Sinai Hospital, (Dr. Porush); Resident in Medicine, Montifiore Hospital. (Dr. Delman); Assistant Resident in Medicine, The Mount Sinai Hospital, (Dr. Feuer).

Footnotes
Submitted for publication Dec. 30, 1960.

Present address: Maimonides Hospital of Brooklyn, 4802 Tenth Ave., Brooklyn 19 (Dr. Porush).

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