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JULIAN D. BOYD, M.D.; HAROLD R. MURDOCK, JR., Ph.D.

Arch Intern Med. 1962;109(6):654-659.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Winter¹ has demonstrated the value of the radioisotope renogram as a screening test for unilateral renal disease. The test provides a graphic record of the serial radioactivity over each kidney after the intravenous injection of a test substance labeled with radioiodine. That record, in turn, gives evidence as to the renal vascularity, the tubular function, and the patency of the excretory tract for the respective kidney. Initially, labeled iodopyracet (Diodrast) was used as the test substance. Due to the fact that iodopyracet is concentrated by the liver, as well as by the kidney, errors of interpretation arose which discredited the radiorenographic procedure in the minds of some observers. However, the recently introduced radioactive-iodohippurate sodium (radio-Hippuran) has proved itself to be an agent which is accumulated only by renal tissue, and which is removed rapidly from the blood by the kidney.²

From the contour of the renographic curve, the . . . [Full Text PDF of this Article]

Author Affiliations
HUNTINGTON, W. VA.

Veterans Administration Hospital.; Formerly Chief of the Intermediate Service and Radioisotope Laboratory: Present address, 1234 Cypress Ave., Santa Ana, Calif. (Dr. Boyd); Principal Scientist (Dr. Murdock).

Footnotes
Submitted for publication June 13, 1961.

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