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A Psychiatric Study of Autoerythrocyte Sensitization

DAVID P. AGLE, M.D.; OSCAR D. RATNOFF, M.D.

Arch Intern Med. 1962;109(6):685-694.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Autoerythrocyte sensitization is a chronic purpuric state, first described in 1955 by Gardner and Diamond.¹ It is the purpose of this paper to demonstrate the frequency of emotional disturbances in patients with this disorder and to suggest that the character traits of these patients play a determining role in the syndrome itself.

Autoerythrocyte sensitization is a disease of adult females, usually becoming clinically manifest after an injury, and characterized by repeated crops of ecchymoses, gastrointestinal bleeding, hematuria, abdominal pain, and neurologic abnormalities. Considerable disability may result from the pain of the cutaneous lesions and from hemarthroses. Gardner and Diamond suspected from the nature of this disorder that the patients had become sensitive to their own blood cells. They produced characteristic lesions by the intracutaneous injection of the patient's own blood or erythrocytic stroma.

Since their initial report, only a few cases have been described.^2-5 However in the last . . . [Full Text PDF of this Article]

Author Affiliations
CLEVELAND

Departments of Psychiatry and Medicine, Western Reserve University School of Medicine and University Hospitals of Cleveland.; Third Year Resident in Psychiatry, Hanna Pavilion of University Hospitals of Cleveland (Dr. Agle); Professor of Medicine, Western Reserve University School of Medicine and Career Investigator of the American Heart Association (Dr. Ratnoff).

Footnotes
Submitted for publication Sept. 20, 1961.

Presented in part at the Annual Meeting of the Association of American Physicians, May 3, 1961.

This study was supported in part by Research Grant H1661C from the National Institutes of Health, U. S. Public Health Service and in part by a grant from the American Heart Association.

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