This Article  • Full text PDF of this Correction  • Original article not online  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (1)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Arch Intern Med. 1962;109(6):774.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In the article, "Corticosteroid Metabolism in Liver Disease", by Drs. Harold Brown and Edwin Englert, Jr., published in the May 1961, issue of the ARCHIVES, editorial changes in the names of the drugs, dihydrocortisone for dihydrohydrocortisone and tetrahydrocortisone for tetrahydrohydrocortisone, caused Compound F to produce derivatives of Compound E instead of its own derivatives. The incorrect sentences should read as follows:

For example, hydrocortisone may be converted to cortisone, cortolone, dihydrohydrocortisone, and 11-β-hydroxy-androstenedione by fibroblasts.³⁵

(Page 777, first column, first paragraph, beginning on line 22)

The first step in the liver is the reduction of hydrocortisone to dihydrohydrocortisone by a specific -hydrogenase in the soluble fraction of the liver cell with stereo specificity to the 5β isomer.⁴³

(Page 777, second column, first paragraph, first sentence)

The next step is the reversible reduction of dihydrohydrocortisone to tetrahydrohydrocortisone by a relatively nonspecific 3-hydroxysteroid dehydrogenase in the soluble fraction of the . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?