This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

II. Further Report on the Comparative Effectiveness of Reserpine, Reserpine and Hydralazine, and Three Ganglion Blocking Agents, Chlorisondamine, Mecamylamine, and Pentolinium Tartrate

VETERANS ADMINISTRATION COOPERATIVE STUDY ON ANTIHYPERTENSIVE AGENTS

Arch Intern Med. 1962;110(2):222-229.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

This report presents the results after one year of follow-up of 759 hypertensive patients who were begun on one of a number of randomized, double blind treatment regimens using various antihypertensive agents. The plan of the study and the methods of procedure have been published previously.¹

In brief, only patients whose diastolic blood pressure levels averaged 90 mm. Hg or above from the fourth through the sixth hospital days were included in the study. These patients were divided into categories of "mild, moderate, and severe" on the basis of the scores obtained in 5 panels: basal diastolic pressure, optic fundi, and abnormalities of the cardiac, renal, and central nervous systems.

Treatment for patients in the mild and half of the moderately severe group consisted of 1 of 3 possible regimens as follows: (1) reserpine 0.5 mg. twice daily for 2 weeks followed by 0.25 mg. twice daily thereafter plus . . . [Full Text PDF of this Article]

Author Affiliations
WASHINGTON, D. C.

Footnotes
Submitted for publication Feb. 26, 1962.

Complete tabular data will be included in the reprints.

Participants: Mark L. Armstrong, M.D.; John L. Bakke, M.D.; Harold Dodge, M.D.; Loyal L. Conrad, M.D.; Edward D. Freis, M.D. (Chairman); Rudolph E. Fremont, M.D.; Walter M. Kirkendall, M.D.; Clifford G. Pilz, M.D.; Eli A. Ramirez, M.D.; David W. Richardson, M.D., and John H. Williams, Jr., B.A.

These included the following Veterans Administration Hospitals: Brooklyn; Chicago West Side; Iowa City; Oklahoma City; Richmond, Va.; San Juan, P.R.; Seattle, and Washington, D.C.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?