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Obstructing Aspergillus Cast of the Renal PelvisReport of a Case in a Patient Having Diabetes Mellitus and Addison's Disease
DAVID E. COMINGS, M.D.;
BERNARD A. TURBOW, M.D.;
DANIEL H. CALLAHAN, M.D.;
SHELDON S. WALDSTEIN, M.D.
Arch Intern Med. 1962;110(2):255-261.
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Although Aspergillus frequently invades tissue, it is also well known for its propensity to form noninvasive, obstructing mycelial masses. These have been observed to occur in pulmonary cavitations as mycetomas1-4 and in bronchiectasis as bronchial casts.3,4 They may produce suffocation,5 asthma or atelectasis,4 or bronchiectasis.1 Pulmonary emboli composed of Aspergillus mycelia have been described.5,6
The following is believed to be the first reported instance of the mycelia of Aspergillus forming an obstructing cast of the renal pelvis. The presence of diabetes mellitus and Addison's disease is of additional interest.
Report of Case
A 27-year-old white woman with known diabetes mellitus was admitted to Cook County Hospital for the first time on Nov. 4, 1960, with complaints of fever and frequent insulin reactions.
She had had labile diabetes since the age of 6. She had required as much as 80 units of isophane insulin daily,
. . . [Full Text PDF of this Article]
Author Affiliations
CHICAGO
Department of Endocrinology, the Hektoen Institute for Medical Research, and the Department of Urology, Cook County Hospital.; Resident in Internal Medicine (Dr. Comings); Resident in Urology (Dr. Turbow); Associate Attending Physician, Department of Urology (Dr. Callahan); Chief, Department of Endocrinology (Dr. Waldstein).
Footnotes
Submitted for publication Nov. 10, 1961.
Supported in part by a grant from the Dr. Leonard H. and Louis D. Weissman Medical Research Foundation.
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