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Relation to Age, Sex, and Breast Feeding

CALVIN M. KUNIN, M.D.

Arch Intern Med. 1962;110(5):676-686.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Escherichia coli have been the subject of a vast number of studies since first characterized more than 75 years ago. They constitute the predominant flora of the colon of many animal species, including man, and have been shown to be of great importance in nutrition, in the metabolism of drugs, in certain diarrheal diseases, and in infections of the urinary tract. Conflicting evidence has been presented concerning the role their products play in the pathogenesis of irreversible shock.^1-3 Under ordinary conditions, these organisms do not appear to disturb the host; in certain circumstances, however, such as during the neonatal period, with hypogammaglobulinemia, localized obstruction, excessive irradiation, adrenal cortical steroid therapy, and neoplasia, they may become invasive and threaten life.⁴ Certain strains which possess hemolytic activity, skin-necrotizing power,⁵ and resistance to the bactericidal activity of serum^6,7 at times appear to be more invasive than others. In general, . . . [Full Text PDF of this Article]

Author Affiliations
CHARLOTTESVILLE, VA.

From the Departments of Preventive Medicine and Medicine, University of Virginia School of Medicine.; Markle Scholar in Medical Science.

Footnotes
Supported in part by Grant E-3602 from the National Institute of Allergy and Infectious Diseases, The National Institutes of Health, U.S. Public Health Service.

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