This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (12)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

GLENN D. LUBASH, M.D.; M. JEANNE FERRARI, M.D.; LAWRENCE SCHERR, M.D.; ALBERT L. RUBIN, M.D.

Arch Intern Med. 1962;110(6):884-887.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

Severe overdosage with sedatives continues to present a serious problem in management. In New York since 1954, sedatives were ranked as the third most common method of committing suicide.¹ In former years the patient rendered comatose by these drugs could be treated only with symptomatic measures and the maintenance of vital functions.² Hemodialysis with the artificial kidney now provides a specific method for removal of the toxic agent.³

Schreiner⁴ has outlined the properties which make drugs suitable for removal by dialysis and reviewed the indications for use of this procedure in intoxicated patients. The latter include: (a) ingestion of a known fatal dose of drug, (b) blood levels in the lethal range, (c) presence of a coexisting or complicating disease, and (d) progressive deepening of anesthesia with clinical deterioration or failure to improve after a period of observation. Difficulties arise, however, when more than one . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

Instructor in Medicine and Advanced Research Fellow of the American Heart Association (Dr. Lubash); Assistant in Medicine (Dr. Ferrari); Instructor in Medicine and Investigator of the Health Research Council of the City of New York (Dr. Scherr), and Associate Professor of Medicine and Established Investigator of the American Heart Association (Dr. Rubin).; Cardiorenal Laboratory, Second (Cornell) Medical Division, Bellevue Hospital, and the Department of Medicine, The New York Hospital-Cornell Medical Center.

Footnotes
Submitted for publication March 19, 1962, accepted for publication April 19, 1962.

Supported in part by grants from the American Heart Association and the Health Research Council of the City of New York (U-1022).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?