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Sickle Cell-Hemoglobin C Crisis Precipitation by Fever TherapyCase Report
CAPT. FRANK R. LECOCQ;
CAPT. JOHN Y. HARPER, JR.
Arch Intern Med. 1963;111(2):149-152.
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Sickle cell-hemoglobin C (S-C) disease has a variable range of clinical severity and may have few symptoms that suggest a generalized disorder. In this patient the diagnosis was suspected because of a hemolytic crisis which was precipitated unintentionally by provoking fever in a Negro female as therapy for a retinopathy. This report discusses the possibility of precipitating a hemolytic crisis by means of fever therapy and emphasizes the importance of ocular findings in S-C disease.
A 30-year-old Negro female was admitted to USAF Hospital, Lackland, in July, 1959, with reduced visual acuity. Three years earlier she had noted a sudden decrease in vision in both eyes and gradual improvement on bed rest. She stated that the vision returned completely in the right eye but remained relatively poor in the left. Approximately one year previous to admission, there was an episode during which the patient experienced temporary bilateral loss of vision.
. . . [Full Text PDF of this Article]
Author Affiliations
USAFMC; USAFMC
From the Internal Medicine Service and the Ophthalmology Service, USAF Hospital, Lackland, USAF Aerospace Medical Center (ATC), Lackland Air Force Base, Texas.
Footnotes
Received for publication April 24, 1961; accepted Oct. 4, 1962.
This paper represents the personal viewpoints of the authors and is not to be construed as a statement of official Air Force policy.
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