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Hepatic Uptake Defect in Patients with "Gilbert's Disease"
JOHN T. GALAMBOS, M.D.;
JOHN R. McLAREN, M.D.
Arch Intern Med. 1963;111(2):214-218.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Radioactive-iodide-labeled iodipamide (R.I.I.) is a simple, practical, and useful liver function test. In general it gives the same information that is obtained by sulfobromophthalein (SBP) retention studies.1 Adequate collimation is of paramount importance when the hepatic uptake is measured after the intravenous injection of R.I.I.
Method
After an overnight fast, the patients were placed in the supine position and 2 scintillation detectors were positioned: one over the heart and the second over the liver. The hepatic monitor was placed at the midclavicular line approximately 3 cm. cephalad to the lower costal margin. Approximately 3 cm. clearance was permitted between the probe and the skin surface. The probe was a Nuclear-Chicago Model DS-5 Serial 1519 to which no additional columniation was added. An intravenous dose of 15µc R.I.I. was administered.
The R.I.I. test is performed as described by McLaren, Galambos, and Weens.1 The hepatic uptake was calculated directly from
. . . [Full Text PDF of this Article]
Author Affiliations
ATLANTA
Associate Professor of Medicine, Emory University School of Medicine (Dr. Galambos); Assistant Professor of Radiology, Emory University School of Medicine (Dr. McLaren).; From the Departments of Medicine and Radiology, Emory University School of Medicine, and Grady Memorial Hospital.
Footnotes
Received for publication June 1, 1962; accepted Aug. 7.
The study was supported in part by NIH Grants H-4714 and C-4697 and by AEC Grant AT-(40-1)-2675.
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