This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (2)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

With Special Reference to Patients with Cancer

ROBERT W. EWER, M.D.; EARL H. ANTES, M.D.; FRANK J. BRAKEL, M.D.

Arch Intern Med. 1963;111(5):634-640.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Pigmentation of the skin associated with neoplastic diseases is seen in intestinal polyposis, carcinoid, melanoma, some lymphomas, and acanthosis nigricans of the so-called malignant type. Of these disorders, only the latter is characterized by cutaneous hyperkeratosis. This brief report describes three patients with an acquired hyperkeratosis of the skin with pigmentation, that differs somewhat from typical acanthosis nigricans, but which is probably closely related to it pathogenically. In each case, the skin lesion was associated with a cancer. An interesting and consistent clinical feature was the ease with which the pigment was stripped from the skin by firm application and immediate removal of adhesive tape.^* Local reduction of pigment was produced. The feature served as a simple bedside test to aid in identification of the disorder.

Report of Cases

CASE 1.—

A Caucasian male, age 41, complained of weight loss, pigmentation of the skin, and weakness of eight months' duration. . . . [Full Text PDF of this Article]

Author Affiliations
EVANSVILLE, IND.

Departments of Medicine, Welborn Clinic and Welborn Memorial Baptist Hospital.

Footnotes
Received for publication June 18, 1962; accepted Dec. 17.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?