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An Unusual Case of Malabsorption

JEROLD M. LOWENSTEIN, MD

Arch Intern Med. 1963;112(2):164.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Radioactive (I¹³¹-labeled) triolein has proved useful in the differential diagnosis of diarrhea, pancreatic disease, and malabsorption syndromes.¹ Its absorption by the intestine, and appearance in the blood, depends on pancreatic lipase which splits fatty acids from triglyceride; absorption, and blood levels, are therefore low in individuals with pancreatic insufficiency, but may also be low in nonspecific malabsorption syndromes.

Absorption of I¹³¹-triolein has been quantified in three ways—by measuring blood levels for several hours,¹ by stool,² or by urine collections.³ In this laboratory, the standard method is measurement of radioactivity in whole blood specimens obtained two, four, and six hours after the patient swallows the I¹³¹-triolein capsule. Normally, a peak level of 6% to 15% in the total blood volume (estimated by weight) is found. Patients with severe chronic pancreatitis may have as little as 0.5% to 2%. In only one person have we failed to find any radioactivity at all . . . [Full Text PDF of this Article]

Author Affiliations
SAN FRANCISCO

Director, Isotope Laboratory, Presbyterian Medical Center.

Footnotes
Received for publication Nov 6, 1962; accepted Jan 31, 1963.

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