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Side Effects of Tetracycline Therapy

BARRY M. SEGAL, MD

Arch Intern Med. 1963;112(2):165-167.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The widespread use of the tetracycline derivatives has led to the recognition of a variety of "side effects." One such triad, photosensitivity, discoloration of the nails, and onycholysis, has been previously reported in a few instances. These reports concerned the effects observed with the use of demethylchlortetracycline (Declomycin)¹,² and chlortetracycline (Aureomycin). The case herein reported developed the above triad during a course of therapy with tetracycline hydrochloride (Achromycin).

Report of a Case

A 60-year-old white male manager of a furniture store was seen on July 18, 1962, with the chief complaints of nocturia, frequency, urgency, and mild incontinence. Past medical history revealed the presence of a lumbar "disc" for 20 years with resulting weakness of the right leg, an appendectomy 15 years ago, and a left inguinal herniorrhaphy 10 years ago. He suffered from mild hay fever, and once he developed a rash after penicillin therapy. There was . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

Medical Resident, Flower-Fifth Avenue Hospital, Metropolitan Hospital Medical Center.

Footnotes
Received for publication Dec 26, 1962; accepted Feb 4, 1963.

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