This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (10)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

JOHN G. HANSEN, MD; RAY S. CRAMPTON, MD

Arch Intern Med. 1963;112(2):171-172.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Death resulting from the intravenous administration of sulfobromophthalein (SBP) has been reported only five times since it was first used by Rosenthal and White to evaluate liver function in 1925.¹,² Not until 1948, when Chambers and Moister reported a near fatal anaphylactic reaction to this drug, was anything more than mild discomfort attributed to its use.³ In 1956, Bjmebae reported the first fatality. Four other deaths have been documented in the literature since then. Of the total of five deaths, two had no previous history of having received sulfobromophthalein, while three had received it at some time prior to the fatal injection.⁴,⁵

This case represents, to the best of our knowledge, the sixth fatal reaction to intravenous SBP dye and the fourth case in which the patient had a previous uncomplicated administration.

Report of Cases

A 49-year-old white man was admitted to Meadowbrook Hospital on Sept 13, 1961, with a chief complaint of weakness and hematemesis. He had been in apparent good health until January, 1961, . . . [Full Text PDF of this Article]

Author Affiliations
HEMPSTEAD, NY

From the Department of Surgery, Meadowbrook Hospital.

Footnotes
Received for publication Feb 8, 1963; accepted Feb 12.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?