This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on Web of Science (5)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

F. JOSEPH FLATLEY, MD; LT MARSHALL E. ATWELL; RICHARD K. McEVOY, MD

Arch Intern Med. 1963;112(3):352-356.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Pseudoxanthoma elasticum (PXE) is a rare, heritable, systemic disorder of elastic tissue and is primarily manifested by abnormalities of the skin, ocular fundus, and cardiovascular system.¹ Gastrointestinal hemorrhage, frequently recurrent, has been reported in association with PXE and may constitute the major hazard to life. Although peptic ulcers, esophageal varices, and ulcerative colitis have been present in some cases, the source of bleeding is most commonly undetermined.^2-15

Involvement of the visceral vessels with elastic tissue degeneration has been postulated as the most likely cause of unexplained bleeding. However, in only five previously reported cases has histologic examination of visceral vessels been performed to substantiate this theory.^16-19

This report describes the clinical, radiological, and pathological findings in a 37-year-old white male with previously undiagnosed PXE who underwent subtotal gastrectomy for persistent gastric hemorrhage.

Report of Case

A 37-year-old, single, white male clerk was admitted to Strong Memorial Hospital . . . [Full Text PDF of this Article]

Author Affiliations
MC, USN; ROCHESTER, NY

Clinical instructor in medicine, University of Rochester School of Medicine and Dentistry, and assistant physician, Strong Memorial Hospital (Dr. Flatley); medical officer, US Naval School of Aviation Medicine, Pensacola, Fla, formerly intern in medicine, Strong Memorial Hospital (Dr. Atwell); clinical instructor in surgery, University of Rochester School of Medicine and Dentistry, and assistant surgeon, Strong Memorial Hospital (Dr. McEvoy).; From the Department of Medicine of the University of Rochester School of Medicine and Dentistry and Strong Memorial Hospital.

Footnotes
Received for publication Jan 3, 1963; accepted April 1.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?