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  Vol. 112 No. 4, OCTOBER 1963 TABLE OF CONTENTS
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Chronic Hypervitaminosis A

Report of a Case in an Adult

JOAQUIN SOLER-BECHARA, MD; JOHN L. SOSCIA, MD

Arch Intern Med. 1963;112(4):462-466.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

Hypervitaminosis A has been described in seven adults since Josephs' first report of a case in a young child in 1944.1 Since then 36 well-documented cases in infants and young children have been reported.2 Knudson and Rothman3 divide hypervitaminosis A into acute and chronic forms as they exist in infants and adults. The acute is self-limited and occurs subsequent to the ingestion of a large single dose of vitamin A. Rodahl and Moore 4 in 1942 described the toxic symptoms of acute hypervitaminosis A in Arctic explorers; this hypervitaminosis A resulted from ingestion of polar bear liver. The chronic form may exist for years without recognition. All adult cases thus far described in the medical literature are of the chronic type.5

The present-day sales of vitamins emphasize the awareness that must be exerted by physicians in the consideration of this clinical entity. Drugstore sales of . . . [Full Text PDF of this Article]


Author Affiliations

NEW YORK

Resident in Internal Medicine (Dr. Soler-Bechara); Chief Resident in Internal Medicine (Dr. Soscia).

From the Department of Medicine, The St. Vincent's Hospital of the City of New York.


Footnotes

Received for publication Feb 8, 1963, accepted Feb 13.



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