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Vivax Malaria Complicated by Aphasia and Hemiparesis
GEORGE J. HILL II, MD;
VERNON KNIGHT, MD;
G. ROBERT COATNEY, PhD;
DEANER K. LAWLESS
Arch Intern Med. 1963;112(6):863-868.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Malaria caused by Plasmodium vivax is a severe illness, yet one which is not ordinarily associated with severe complications or death. For this reason, vivax malaria has long been referred to as "benign tertian malaria."
Transmission of malaria from man to man has been carried out since 1917, to produce "fever therapy" for neurosyphilis and certain chronic psychoses. These induced malaria infections have incidentally provided a vast amount of valuable information concerning the natural history of human malaria. The development of synthetic antimalarial drugs and studies of immunity to malaria have been greatly facilitated by observations on illnesses induced in neuropsychiatric patients and volunteers.
From 1944-1962, malaria has been induced either by the inoculation of parasitized blood or by the bites of infected mosquitos in approximately 2,000 volunteers at the Federal Penitentiary, Atlanta, and the Federal Correctional Institution, Seagoville, Tex, without resulting in death or in a cardiovascular complication
. . . [Full Text PDF of this Article]
Author Affiliations
BETHESDA, MD
Laboratory of Clinical Investigation and Laboratory of Parasitic Chemotherapy, National Institute of Allergy and Infectious Diseases, National Institutes of Health.
Footnotes
Received for publication July 2, 1963; accepted July 25.
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