This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (13)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

JORGE O. JUST-VIERA, MD

Arch Intern Med. 1964;113(1):122-128.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

I. Introduction

Clubbing is a frequently observed, often misdiagnosed, and inadequately explained phenomenon recognized since antiquity. Hippocrates ^1,2 first described it in empyema, noting that the "nails of the hands are bent, the fingers are hot especially their extremities." ³ Aretaeus associated clubbing with internal disease, and Aurelianus emphasized the increase in volume of the fingertips.⁴ Pigeaux ⁵ published in 1832 the first definite work on the subject, and Marie wrote his classic article in 1890.⁶

Known by many different names, clubbing is most commonly referred to as pulmonary hypertrophic osteoarthropathy.

II. Definition

Clubbing is a clinical sign observed in the terminal phalanges which may or may not be associated with a pathological condition. If seen during disease, clubbing constitutes the early stage of a process of unknown pathogenesis and etiology in which the underlying condition causes changes in the soft tissues, in the periosteum, in the bone . . . [Full Text PDF of this Article]

Author Affiliations
BALTIMORE

From the Department of Surgery, University of Maryland School of Medicine.

Footnotes
Received for publication April 11, 1963; accepted July 15.

Pangborn Fellow in Peripheral Vascular Diseases.

Supported by the Pangborn Foundation Fund.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?