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Multifocal Carcinoma Occurring After Long Remission of Colitis

RICHARD G. FARMER, MD; CHARLES H. BROWN, MD

Arch Intern Med. 1964;113(1):153-157.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A relationship between chronic ulcerative colitis and the subsequent development of carcinoma of the colon has been well established.^1-9 It has been emphasized that onset of ulcerative colitis in childhood,^8-14 duration of activity of the colitis,^8-10,15 and severity of symptoms¹⁰ appear to be predisposing factors to neoplastic change. A relationship between pseudopolyposis and malignant degeneration has not been confirmed.^7,10,15-17 Although it has been stated that ulcerative colitis may be quiescent at the time of recognition of colonic carcinoma,^15,17,18 in our opinion, this point has not received sufficient emphasis. Accordingly, we are reporting a case in which, after more than 16 years of total remission of ulcerative colitis, con- firmed both clinically and proctoscopically, carcinoma of the colon was detected on routine examination.

Report of a Case

A 23-year-old man was initially examined at the Cleveland Clinic on July 3, 1933, because of diarrhea consisting . . . [Full Text PDF of this Article]

Author Affiliations
CLEVELAND

From the Department of Gastroenterology, The Cleveland Clinic Foundation.

Footnotes
Received for publication July 18, 1963; accepted Aug 5.

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