This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (8)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Z. FARID, MD; A. S. PRASAD, MD, PhD; A. R. SCHULERT, PhD; H. H. SANSTEAD, MD; ABOU SHADI EL ROOBY, MD

Arch Intern Med. 1964;113(1):37-41.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Bilharzial hepatic fibrosis, usually accompanied by marked enlargement of the spleen, leukopenia, thrombocytopenia, and hypochromic anemia, is endemic in Egypt.¹ The possibility that the enlarged bilharzial spleen may acquire hypersplenic activity and cause hemolytic anemia has been discussed by workers from Egypt² and elsewhere³; however, no convincing evidence to prove this has been reported in the literature. Recently, Jandl et al⁴ have described a method for determining the sites of red cell destruction by using Cr⁵¹. We have used this technique to study the Cr⁵¹ red cell half-survival time and the uptake of radioactivity by the spleen, liver, and precordium in four patients with proved bilharzial hepatosplenomegaly. In addition, other hematological and biochemical tests were carried out. In none of these patients did we produce evidence of anemia due to hypersplenism.

Methods and Materials

Four patients with marked hepatosplenomegaly were studied. Liver biopsy, performed . . . [Full Text PDF of this Article]

Author Affiliations
CAIRO, EGYPT, AND NASHVILLE, TENN

From the Medical Department, United States Naval Medical Research Unit No. 3, and Kasr El Aini Faculty of Medicine, Cairo University, Cairo, Egypt, UAR, and departments of biochemistry and medicine, Vanderbilt University School of Medicine, Nashville, Tenn.

Footnotes
Received for publication Feb 13, 1963; accepted March 4.

The opinions and assertions contained herein are the private ones of the authors and are not to be construed as official or reflecting the views of the Navy Department, the naval service at large, or the Egyptian Ministry of Public Health.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?