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Hematocrit Values in Coronary Artery Disease
C. LOCKARD CONLEY, MD;
R. PATTERSON RUSSELL, MD;
CAROLINE B. THOMAS, MD;
PHILIP A. TUMULTY, MD
Arch Intern Med. 1964;113(2):170-176.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Recent reports suggest that the hematocrit value may be a significant factor in predisposition to coronary thrombosis.1-4 Hematocrit values of both men and women with myocardial infarction were observed to be higher on the average than those of age-matched control subjects. The data led to the proposal that the red cell volume of patients with coronary artery disease should be reduced by venesection in an effort to prevent thrombosis. An editorial in the Journal of the American Medical Association5 notes that these "stirring reports... tend to pick up the threads of medieval medicine...", and raise the question whether phlebotomy may be "an ancient procedure turning modern."
In an independent study of the hematocrit values of normal men and of men with acute myocardial infarction we were unable to corroborate the earlier reports and found no correlation between hematocrit value and occurrence of coronary thrombosis.
Methods
Four groups of
. . . [Full Text PDF of this Article]
Author Affiliations
BALTIMORE
From the Department of Medicine, The Johns Hopkins University School of Medicine and Hospital.
Footnotes
Received for publication Aug 23, 1963; accepted Sept 10.
Presented before Topics in Clinical Medicine, The Johns Hopkins University School of Medicine and Hospital, Baltimore, May 17, 1963.
Professor of Medicine (Drs. Conley and Tumulty); Instructor in Medicine (Dr. Russell); Associate Professor of Medicine (Dr. Thomas).
This study was supported in part by training grant T1 AM-5260 and research grant HE-01891, from the National Institutes of Health, US Public Health Service.
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