This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on Web of Science (5)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

W. D. STONE, BM, MRCP

Arch Intern Med. 1964;113(2):208-212.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The clinical features of massive venous thrombosis, or phlegmasia cerulea dolens, have been well documented in the last 15 years. The onset is usually sudden and may or may not follow the commoner mild form of thrombophlebitis. The affected limb, usually a leg, becomes grossly swollen and cyanotic, often with cutaneous hemorrhages and bullae. Arterial pulsations are reduced, the superficial veins are distended, and shock is a common complication. Gangrene of part of the limb develops in 50% of cases, and the over-all mortality is about 25%.⁶

It is generally agreed that this picture appears only when almost the whole venous drainage of the limb is obstructed, although venospasm may contribute to the obstruction in some cases.^7,8 Experimentally, gangrene has only been produced by blocking nearly all the veins draining the part.^4,9,10 There is commonly malignant disease or inflammation in the pelvis, and some cases have followed . . . [Full Text PDF of this Article]

Author Affiliations
LONDON

St. Thomas' Hospital.

Footnotes
Received for publication June 24, 1963; accepted Sept 4.

Present address: The Johns Hopkins Hospital, Baltimore.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?