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Muscular Dystrophy in Man and DuckA Comparative Study
R. H. RIGDON, MD;
GLENN A. DRAGER, MD
Arch Intern Med. 1964;113(4):586-597.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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A spontaneously occurring myopathy that resembles in many ways muscular dystrophy in man has been observed in a strain of white Pekin ducks.1,2 Of these ducks, 10% developed contractures, usually between the 7th and 21st day of life, in one or both extremities.3 Many had muscular weakness and morphologic changes in the muscle without contractures. The histologic lesions in the striated muscle were characterized by focal areas of necrosis within individual muscle fibers.1-3 Genetic studies now in progress would suggest that transmittal does occur.
A variety of agents have produced degenerative lesions in the striated muscle of different laboratory animals: irradiation,4,5 a chemical,6 bacterial infections,7 viruses,8 vitamin deficiency,9 and massive doses of cortisone.10,11 A genetic disease has been described in which there are degenerative lesions in the striated muscle of the mouse,12 hamster,13,14 and chicken.15-17
Progressive muscular dystrophy
. . . [Full Text PDF of this Article]
Author Affiliations
GALVESTON, TEX
Professor of Pathology (Dr. Rigdon); Associate Professor of Neurology and Psychiatry (Dr. Drager).; Departments of pathology and neurology and psychiatry, The University of Texas Medical Branch.
Footnotes
Received for publication Sept 5, 1963; accepted Sept 17.
This study was supported by US Public Health Service grant NB-02951-03, from the National Institutes of Neurological Diseases and Blindness, and by the Liberty Muscular Dystrophy Foundation.
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