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W. J. FESSEL, MRCP; HOWARD D. KURLAND, MD; ROBERT P. CUTLER, MD

Arch Intern Med. 1964;113(5):669-671.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The purpose of this paper is to confirm our previous observations ^2-5,7 that sera of some psychiatric patients contain higher than normal macroglobulin levels and that schizophrenic and manic-depressive patients' sera may be differentiated by the higher macroglobulin content of the one and the lower amount in the other.⁹

The earlier studies, on sera of schizophrenic and manic-depressive patients at two separate hospitals in California, were not all made blindly. For complete assurance that the findings were valid, the present examinations were made on coded sera obtained from carefully studied patients in Chicago.

Materials and Methods

Subjects.

—We studied 13 manic-depressive and 14 schizophrenic patients at Evanston Hospital, Chicago. All were outpatients except for two schizophrenic subjects, and all except three were personal patients of one of us (R.P.C.) who had followed most of them for several years. At the time of the drawing of their blood, the patients . . . [Full Text PDF of this Article]

Author Affiliations
SAN FRANCISCO; OAKLAND, CALIF; CHICAGO

From the departments of psychiatry and medicine, University of California School of Medicine, San Francisco; the Neuropsychiatric Service and Clinical Investigation Center, US Naval Hospital, Oakland, Calif; and the Department of Neurology and Psychiatry, Northwestern University Medical School, Chicago.

Footnotes
Received for publication Sept 12, 1963; accepted Nov 15.

Supported in part by USPHS grant MH-04581-02 and in part by contract Nonr-222 (51) (NR105 156) between Office of Naval Research, Department of the Navy, Washington, DC, and the Department of Medicine, University of California Medical Center, San Francisco.

Opinions or assertions contained herein are private ones of the authors and not to be construed as official or necessarily as reflecting views of the Medical Department of the Navy or Naval Service at large.

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