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Polyneuropathy Following Exposure To InsecticidesTwo Cases of Polyneuropathy With Albuminocytologic Dissociation in the Spinal Fluid Following Exposure to DDD and Aldrin and DDT and Endrin
R. B. JENKINS, MB, B Chir;
CHAPEL HILL, NC;
J. F. TOOLE, MD
Arch Intern Med. 1964;113(5):691-695.
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A cause-and-effect relation between exposure to insecticides and subsequent development of polyneuropathy is very difficult to prove even when strongly suspected. However, in the two cases described below such a relation is so probable that we believe their full report is warranted. Our two patients had albuminocytologic dissociation in the spinal fluid and might have been considered to be suffering from a sporadic form of the Guillain-Barré syndrome (acute idiopathic polyneuritis) of cryptogenic origin had not the close association between exposure to insecticide and neurologic manifestations made an etiologic relationship probable. Despite the enormous quantities of insecticides used annually, case reports of polyneuropathy caused by them are few, perhaps because of their rarity, but perhaps also because of failure of physicians to consider insecticides as a possible causative agent.
CASE 1
—A 13-year-old boy was admitted to the North Carolina Baptist Hospital for evaluation of weakness and paresthesias. He was
. . . [Full Text PDF of this Article]
Author Affiliations
WINSTON-SALEM, NC
Footnotes
Received for publication Oct 12, 1963; accepted Nov 8.
Assistant Professor of Neurology, University of North Carolina School of Medicine, Chapel Hill (Dr. Jenkins); Professor of Neurology, Bowman Gray School of Medicine, Winston-Salem (Dr. Toole).
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