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SAMUEL CHARACHE, MD; STUART N. RICHARDSON, MD

Arch Intern Med. 1964;113(6):844-849.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A 66-year-old woman has both sickle cell anemia and pseudoxanthoma elasticum. Her case is of interest not only because of the coexistence of two genetically determined disorders, but because her advanced age appears to reflect significant differences between accounts of the natural history of sickle cell anemia and the disease as it is currently encountered in North America.

Report of Case

A 66-year-old Negro woman entered The Johns Hopkins Hospital in January, 1962, because of pain and swelling of the left ankle. In 1912, at the age of 16, she had been admitted to this hospital twice for chills, fever, and "pain all over." Similar pains had occurred at intervals since her early childhood. On physical examination at the time of her first admission she was pale, the heart was enlarged, and the spleen was palpable. Hemoglobin concentration was recorded as 46% (Sahli technique). During adolescence, she first noted yellowish . . . [Full Text PDF of this Article]

Author Affiliations
BALTIMORE

From the Department of Medicine, The Johns Hopkins University and Hospital.

Footnotes
Received for publication Sept 16, 1963; accepted Nov 21.

Supported by USPHS grants HE-02799, T1-AM-5260, and OG-11.

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