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Keratosis Palmaris et Plantaris
HERBERT L. FRED, MD;
RICHARD G. GIESER, MD;
WILLIAM R. BERRY, BS;
JOHN M. EIBAND, MD
Arch Intern Med. 1964;113(6):866-871.
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Keratosis palmaris et plantaris (KPP), also referred to as tylosis and by many other synonyms,* is a heredofamilial ectodermal defect characterized by hyperkeratosis of the palms and soles. Since KPP ordinarily is not accompanied by systemic manifestations or specific lesions of internal organs, the internist rarely encounters the syndrome. Therefore, the purpose of this report is to review briefly the subject of KPP and to present one of the most extraordinary examples of this malady ever recorded.
Report of a Case
A 56-year-old Latin-American mechanic was admitted to The Ben Taub General Hospital because of hematemesis of one day's duration. There had been no associated abdominal pain, jaundice, black stools, weight loss, recent intake of alcohol, or previous episodes of gastrointestinal bleeding. The patient had been a "spree drinker" in the past.
The only significant feature of the past medical history was that of palmar and plantar hyperkeratosis. Neither the
. . . [Full Text PDF of this Article]
Author Affiliations
HOUSTON
Assistant Professor of Medicine, Baylor University College of Medicine, and Director of Medical In-Patient Service, The Ben Taub General Hospital (Dr. Fred); Intern, Medical Service, The Ben Taub General Hospital (Dr. Gieser); Junior Student, Baylor University College of Medicine (Mr. Berry); Instructor in Medicine, Baylor University College of Medicine (Dr. Eiband).
From the Department of Medicine, The Ben Taub General Hospital and the Baylor University College of Medicine.
Footnotes
Received for publication Sept 17, 1963; accepted Oct 15.
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