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Correlation of Split Renal-Function Tests and Pressor Assays of Renal Venous Blood in Hypertensive Patients

CAPT JOHN J. McPHAUL, JR., MC; CAPT DUNCAN A. McINTOSH, MC; CAPT LESTER F. WILLIAMS, MC; MAJ EMIL J. GRITTI, MC; MAJ WILLIAM G. MALETTE, MC; ARTHUR GROLLMAN, MD, PhD

Arch Intern Med. 1965;115(6):644-651.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ALTHOUGH several procedures have been recommended for the detection of patients suffering from correctable renal hypertension, none has proved to be adequate for the purpose, and the decision to undertake surgical intervention is based frequently on an educated guess. Stenosis of the renal artery remains the most commonly accepted indication of the possible presence of surgically remediable hypertension.^1-13 However, this lesion is encountered frequently in normotensive patients¹⁴ and its repair is often not followed by reduction of the elevated blood pressure. Another commonly used diagnostic procedure for detecting correctable renal hypertension utilizes the decreased volume and sodium content of the urine of the affected kidney, as described first by Connor et al ^1,2 and modified by Dustan et al,³ Stamey et al,¹³ Rapaport,¹⁵ Birchall et al,¹⁶ and others. This procedure likewise has failed to provide a decisive method for detecting patients with unilateral renal disease. The histological appearance of the . . . [Full Text PDF of this Article]

Author Affiliations
LACKLAND AIR FORCE BASE, TEX

From the departments of medicine, surgery, and urology of the Wilford Hall USAF Hospital, Aerospace Medical Division (AFSC). Present address: Department of Surgery, University of Kentucky, School of Medicine, Lexington (Dr. Malette); Professor and Chairman of the Department of Experimental Medicine, University of Texas Southwestern Medical School, Dallas (Dr. Grollman).

Footnotes
Received for publication Sept 10, 1964; accepted Dec 4.

Presented in abstract form by captains McPhaul and McIntosh (Clin Res 11:171, 1963), and read before the American Federation for Clinical Research, Atlantic City, NJ, April 10, 1963.

The opinions expressed are those of the authors and do not necessarily express the policies of the Air Force Medical Service.

Reprint requests to 5323 Harry Hines Blvd, Dallas, Tex 75235 (Dr. Grollman).

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