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Cerebral Salt-Wasting Associated With the Guillain-Barré Syndrome
LT CDR WILLIAM C. COOPER, MC;
LT CDR IRVING J. GREEN, MC;
SAN-PIN WANG, MD
Arch Intern Med. 1965;116(1):113-119.
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INAPPROPRIATE secretion of antidiuretic hormone has been implicated as the cause of the hyponatremia and renal salt-wasting associated with certain cases of intracranial and intrathoracic disease. Cases of traumatic, infectious, and neoplastic intracranial disease, and of neoplastic thoracic disease have been associated with the salt-wasting syndrome.1-6 The following is a report of the simultaneous occurrence in a patient of an illness clinically indistinguishable from the Guillain-Barré syndrome and of an electrolyte disturbance marked by transient loss of renal sodium-conserving ability, plasma hypo-osmolality, and plasma hyponatremia. Immunologic features of this patient's illness suggested to us that the etiology of the polyradiculoneuropathy was hypersensitivity to viral antigens.
Report of a Case
A 32-year-old Taiwanese man, a virology technician at the US Naval Medical Research Unit No. 2 (NAMRU-2), was admitted to Taiwan University Hospital on Sept 16, 1961, with the chief complaint of walking disturbance and pain in the left
. . . [Full Text PDF of this Article]
Author Affiliations
USN; USN; TAIPEI, TAIWAN, REPUBLIC OF CHINA
From the Clinical Investigation Department, US Naval Medical Research Unit No. 2 (NAMRU-2). Clinical investigator (Dr. Cooper) and virologist (Drs. Green and Wang). Present addresses: Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, Mass (Dr. Cooper); University of California Medical Center, Los Angeles (Dr. Green); Department of Preventive Medicine, University of Washington School of Medicine, Seattle (Dr. Wang).
Footnotes
Received for publication Dec 18, 1964; accepted Jan 15, 1965.
Read before the First Asian and Oceanian Congress of Neurology, Tokyo, Oct 10, 1963.
The opinions and assertions contained herein are those of the authors and are not to be construed as official or reflecting the views of the Navy Department or the Naval Service at large.
Reprint requests to Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, Mass 02139 (Dr. Cooper).
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