 |
|
Leukemoid Reactions to Tuberculosis
JEREMIAH J. TWOMEY, MB;
BYRD S. LEAVELL
Arch Intern Med. 1965;116(1):21-28.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
|
|
|
TUBERCULOSIS has been associated with a variety of hematological abnormalities. These include hypoplasia of the bone marrow,1,2 myelofibrosis,3-5 and polycythemia.6 Tuberculosis is sometimes associated with a leukemoid reaction which must be differentiated from leukemia. In 1911 Coley and Ewing,7 from postmortem studies, first drew attention to the leukemoid response which may be evoked by tuberculosis. The association was first made antemortem by Mills and Townsend 8 in 1937. We have found only 38 reports of patients who had leukemoid reactions to tuberculosis which fulfilled the following criteria: (1) tubercle bacilli had to be demonstrated and (2) an excessive leukocytosis or an abnormal shift towards immaturity in the peripheral blood or in the bone marrow. A diagnosis of leukemia was considered to be excluded if a lasting hematologic recovery occurred or if visceral infiltration with leukocytes could not be demonstrated at autopsy.
It is the purpose of this paper to discuss
. . . [Full Text PDF of this Article]
Author Affiliations
CHARLOTTESVILLE, VA
From the Department of Internal Medicine, University of Virginia Hospital, Charlottesville. Captain Twomey is presently Chief of Hematology at the William Beaumont General Hospital, El Paso, Tex.
Footnotes
Received for publication Oct 2, 1964; accepted Dec 2.
Read in part before the Clinical and Climatological Meeting, Hot Springs, Va, November, 1963.
Reprint requests to Box 607 William Beaumont General Hospital, El Paso, Tex 79920 (Captain Twomey).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
|
