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Treatment of Five Patients With Long-Term Antibiotic Therapy

RICHARD H. SUHS, MD; HARRY F. DOWLING, MD; GEORGE G. JACKSON, MD

Arch Intern Med. 1965;116(1):29-38.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ACQUIRED hypogammaglobulinemia is characterized by frequent respiratory-tract infections and may be associated with chronic infection of the bronchial tree. Continuous therapy with -globulin, sulfonamides, or antibiotics has been advocated for the prevention of acute exacerbations of bronchial infection. In this paper five patients with acquired hypogammaglobulinemia, given antibiotics as prophylactics, are reported and other adequately documented cases that have been reported are reviewed.

Method of Study

Our five patients¹ are part of a larger group observed in a long-term study of chronic bronchitis and bronchiectasis to determine whether the continuous administration of certain antibiotics would diminish bacterial infections and retard the progress of the disease. Among 155 patients examined, four were found to have hypogammaglobulinemia.² Each of these patients was started on a different therapeutic regimen, which was later changed if necessary. These will be described in detail later. One additional patient (patient 5) with hypogammaglobulinemia was . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the University of Illinois Research and Educational Hospitals, the Department of Medicine, University of Illinois. Professor of Medicine and Head of Department: (Dr. Dowling); Professor of Medicine (Dr. Jackson). Formerly US Public Health Service Fellow in Infectious Diseases, University of Illinois College of Medicine, Department of Medicine (Dr. Suhs).

Footnotes
Received for publication Dec 28, 1964; accepted Jan 13, 1965.

Reprint requests to 840 S Wood St, Chicago 60612 (Dr. Dowling).

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