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T-P PhenomenonAn Electrocardiographic Clue to Unsuspected Alkalosis
CARL S. ALEXANDER, MD
Arch Intern Med. 1965;116(2):220-227.
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IN THE COURSE of examining the charts of many alcoholic patients, an unusual electrocardiographic pattern was frequently observed which had two main features: (1) sinus tachycardia, and (2) relative prolongation of the QT interval (QTc), which in most cases was actually due to relative prolongation of the ST segment. Thus, the delayed T wave is closely followed by the next P wave, or the P wave may even begin on the downstroke of a T wave (Fig 1), and since this double peak strikes the eye at first glance it has been called T-P approximation or simply T-P. These changes which are illustrated best in leads II, III, AVF, and left precordial leads, have been found to be a reliable indicator of metabolic, respiratory, or mixed alkalosis. Since the electrocardiogram is usually obtained early in the course of a diagnostic survey, it has been helpful in directing attention to
. . . [Full Text PDF of this Article]
Author Affiliations
MINNEAPOLIS
From the Minneapolis Veterans Administration Hospital and the Department of Medicine, University of Minnesota. Chief, Cardiovascular Section, Veterans Administration Hospital and Associate Professor, Department of Medicine, University of Minnesota.
Footnotes
Received for publication Dec 16, 1964; accepted Jan 13, 1965.
Read before the 37th Annual Scientific Session of the American Heart Association, Atlantic City, NJ, Oct 25, 1964.
Reprint requests to 54th St and 48th Ave S, Minneapolis, Minn 55417.
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