 |
|
Familial Auto-Immune Hemolytic Anemia
CHARLES E. DOBBS, MD
Arch Intern Med. 1965;116(2):273-276.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
|
|
|
THE FAMILIAL occurence of auto-immune hemolytic anemia has been rarely observed, and only three convincing reports have been published.1-3 Extensive serological examination of asymptomatic family members has been undertaken in one instance.3 The observation that there was an increased incidence of serological abnormalities suggests that genetic factors may play a more significant role in the pathogenesis of auto-immune hemolytic anemia than has been previously recognized.
In 1963 a brother and sister with severe Coombs' positive hemolytic anemia were evaluated by the Division of Hematology, Washington University, School of Medicine. A third sibling, who died in 1949, had a history compatible with hemolytic anemia. The implication of these observations led to an evaluation of a number of consanguineous and nonconsanguineous family members. The case histories of the three affected siblings together with information compiled in the study of the asymptomatic relatives comprise the substance of this report.
Subjects and
. . . [Full Text PDF of this Article]
Author Affiliations
MIAMI, FLA
From the departments of medicine, Washington University School of Medicine and the University of Miami School of Medicine. Dr. Dobbs is a US Public Health Service Trainee in Hematology.
Footnotes
Received for publication Dec 1, 1964; accepted Jan 27, 1965.
Reprint requests to 1600 NW Tenth Ave, Miami, Fla 33136.
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
|
