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Treatment With Immune Human Plasma

DAVID S. FEINGOLD, MD; FRANK OSKI, MD

Arch Intern Med. 1965;116(3):326-328.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Infections NFECTIONS with organisms of the genus Pseudomonas have become a serious nosocomial problem.¹ These bacteria are frequently resistant to antimicrobial drugs. The treatment of these infections with commercial pooled _-globulin (Cohn fraction II) has had, at best, limited success. In this report of a case, evidence is presented which suggests that plasma from a patient convalescing from a Pseudomonas infection may constitute effective therapy. The possible basis for the efficacy of such therapy is discussed.

Report of Case

A 5-year-old Caucasian boy was admitted to the Hospital of the University of Pennsylvania for the first time on Oct 29, 1963 with a two day history of vomiting, shaking chills, and fever. The patient had had aplastic anemia of unknown etiology for the previous six months. He had been treated for the past five months with testosterone propionate and prednisone. On this hormonal therapy the patient had shown . . . [Full Text PDF of this Article]

Author Affiliations
PHILADELPHIA

From the departments of research medicine and pediatrics, University of Pennsylvania School of Medicine, Philadelphia. Instructor, Department of Research Medicine and presently at Beth Israel Hospital, Boston (Dr. Feingold) and Associate, Department of Pediatrics, (Dr. Oski).

Footnotes
Received for publication November, 1964; accepted Jan 27, 1965.

Reprint requests to Beth Israel Hospital, 330 Brookline Ave, Boston, Mass 02215 (Dr. Feingold).

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