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Clinical and Pathologic Features

MAURICE BERNSTEIN, MD; HUGH A. EDMONDSON, MD; BENJAMIN H. BARBOUR, MD

Arch Intern Med. 1965;116(4):491-498.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

WE HAVE STUDIED two patients with a febrile illness whose clinical features resembled those of a primary disorder of the liver. One had frank jaundice; both had splenomegaly. We believe a report of these cases will be of general interest because each patient had serologic evidence of Q fever and each had a characteristic alteration of liver histology. In reviewing the literature on hepatic involvement in Q fever, we noted that reports by Gerstl et al,¹ Picchi et al,² Powell,³ and Gallaher⁴ mention lesions of the liver similar to those observed in our two patients. Of clinical interest is the observation that some patients with Q fever have symptoms and findings referable to the liver without any discernible disease of the lungs.

Report of Cases

CASE 1.

—A 41-year-old white woman was admitted to the Los Angeles County Hospital on Feb 2, 1960, because of fever and jaundice. In the . . . [Full Text PDF of this Article]

Author Affiliations
LOS ANGELES

From the departments of medicine and pathology, School of Medicine, University of Southern California and the Los Angeles County Hospital. Head Physician Internal Medicine, Los Angeles County Hospital (Dr. Bernstein); Professor of Pathology (Dr. Edmondson) and Assistant Professor of Medicine (Dr. Barbour), School of Medicine, University of Southern California.

Footnotes
Received for publication May 3, 1964; accepted March 4, 1964.

Reprint requests to 1200 N State St, Los Angeles, Calif 90033 (Dr. Edmondson).

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