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JOHN C. KULIS, MD

Arch Intern Med. 1965;116(4):559-561.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

CHEMICALS can cause thrombocytopenia either as the initial manifestation of an aplastic anemia or as selective thrombocytopenia without anemia and neutropenia. If exposure to the toxic chemical is immediately stopped, the subsequent thrombocytopenia may not develop.

This paper documents two cases of selective thrombocytopenia associated with the use of chemical agents. The patients were exposed to insecticides. The first had a single, acute exposure where as the second was repeatedly exposed in the performance of his occupation.

Because of the widespread use of such substances, I feel that this information should be brought to the attention of physicians, in that it illustrates the need for thorough investigation into all possible chemical contacts. The chemical agents can be drugs administered for therapeutic purposes or chemicals used in industry and in the home.

There are many drugs, especially the newer ones, which have been implicated in the production of blood dyscrasias, such . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Swedish Covenant Hospital, Chicago. Clinical Instructor of Medicine, University of Illinois.

Footnotes
Received for publication Feb 6, 1965; accepted April 6.

Reprint requests to 4013 N Milwaukee Ave, Chicago, Ill 60641.

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